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Naturally selected mutations of SARS-CoV-2 easily duplicated in vitro – News-Medical.Net

In a recent and timely paper, currently available on the bioRxiv preprint server, researchers from Israel and France demonstrated how in vitro evolution of the…

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In a recent and timely paper, currently available on the bioRxiv* preprint server, researchers from Israel and France demonstrated how in vitro evolution of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) receptor-binding domain (RBD) follows contagious mutation spread – but can also generate an efficient infection inhibitor.
Both structural and functional research endeavors have revealed that a single RBD of the SARS-CoV-2 homotrimer spike glycoprotein is sufficient for interaction…

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