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Compounds block stress-enhanced reacquisition of nicotine in rats – News-Medical.net

Stress is a major cause of relapse after people quit smoking. Worrying situations, such as money or relationship problems, can affect neurotransmitter levels in…

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Stress is a major cause of relapse after people quit smoking. Worrying situations, such as money or relationship problems, can affect neurotransmitter levels in the brain, leading former smokers to reach for a cigarette. Now, researchers reporting in ACS Pharmacology & Translational Science have discovered that compounds that activate γ-aminobutyric acid (GABA) receptors in the brain can keep rats from self-administering increased levels of nicotine during stressful conditions in an animal model…

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