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Novel short ACE2 isoform may influence SARS-CoV-2 susceptibility – News-Medical.Net

A study led by researchers at the University of Southampton, UK, has identified a novel short isoform of the full-length receptor that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) uses to gain entry to host cells.

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A study led by researchers at the University of Southampton, UK, has identified a novel short isoform of the full-length receptor that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) uses to gain entry to host cells.
The short isoform of angiotensin-converting enzyme 2 (ACE2), which the authors have called “short ACE2,” is expressed in the airway epithelium – the main infection site for SARS-CoV-2.
Lead authors Cornelia Blume, Claire L Jackson, and colleagues say that the short AC…

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