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Looking beyond COVID-19’s spike protein for the next wave of vaccines – FierceBiotech

Most ongoing vaccine development efforts against the novel coronavirus focus on the spike protein on the surface of SARS-CoV-2. But a team led by immuno-oncology specialist TScan Therapeutics found that memory CD8+ T cells from recovered patients mainly targe…

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Most ongoing vaccine development efforts against the novel coronavirus use the spike protein on the surface of SARS-CoV-2 in the hopes of inducing neutralizing antibodies that can directly block the virus from infecting healthy cells. But there could be one major caveat to that approach: The antibody response to the virus, mediated by B cells of the immune system, appears to wane quickly.
Thats why a research team led by immuno-oncology biotech TScan Therapeutics turned to another key component…

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