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Rapid Decay of Anti–SARS-CoV-2 Antibodies in Persons with Mild Covid-19 – nejm.org

Correspondence from The New England Journal of Medicine — Rapid Decay of Anti–SARS-CoV-2 Antibodies in Persons with Mild Covid-19

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A recent article suggested the rapid decay of antiSARS-CoV-2 IgG in early infection,1 but the rate was not described in detail. We evaluated persons who had recovered from Covid-19 and referred themselves to our institution for observational research. Written informed consent was obtained from all the participants, with approval by the institutional review board. Blood samples were analyzed by enzyme-linked immunosorbent assay (ELISA) to detect antiSARS-CoV-2 spike receptor-binding domain IgG.2 …

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