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Mouse model of fatal COVID-19 developed for vaccine and drug testing – News-Medical.Net

Now, a new study published on the preprint server bioRxiv in July 2020 presents an engineered transgenic mouse that reproduces the functional and clinical characteristics of severe human SARS-CoV-2 infection.

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As the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spreads throughout the world infecting millions, scientists are still frantically searching for an effective vaccine or antiviral.
One obstacle in SARS-CoV-2 vaccine development is the absence of a small animal model that undergoes infection with SARS-CoV-2 in a manner similar to humans.
Now, a new study published on the preprint server bioRxiv* in July 2020 presents an engineered transgenic mouse that reproduces the functiona…

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